Molecules
Jan Šegina, Luka Ciber, Helena Brodnik, Franc Požgan, Jurij Svete, Bogdan Štefane, Uroš Grošelj
he endo- and exo-N-heterocyclic carbene precursors based on camphor were prepared diastereoselectively in five synthetic steps starting from (1S)-(+)-ketopinic acid. The obtained N-heterocyclic carbene precursors were investigated in an asymmetric benzoin reaction. All new compounds were fully characterized, and the absolute configurations were determined via X-ray diffraction and NOESY measurements.
Read article: Molecules, 2023, 28(24), 7973
