Molbank
Mišel Hozjan, Luka Ciber, Franc Požgan, Jurij Svete, Bogdan Štefane, Uroš Grošelj
Organocatalyzed synthesis of tert-butyl 2-amino-3-cyano-5-oxo-4-phenyl-5,7-dihydropyrano[2,3-c]pyrrole-6(4H)-carboxylate, prepared from Boc-tetramic acid and benzylidenemalononitrile, is disclosed. Two bifunctional noncovalent organocatalysts were employed, yielding the product as a racemic mixture in both cases. The structure of the new synthesized compound was confirmed by high resolution mass-spectrometry, 1H- and 13C-NMR, HSQC, and IR spectroscopy.
Read article: Molbank, 2023, 2023(1), M1575